Idiopathic multicentric Castleman’s disease

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Idiopathic Multicentric Castleman’s Disease with Normal Interleukin-6 Levels

Multicentric Castleman’s disease (MCD) is a rare systemic lymphoproliferative disorder characterised by polylymphadenopathy, B-symptoms and classical lymph node histological findings. Hypercytokinemia, particularly interleukin-6 (IL-6), secondary to human herpes virus-8 (HHV-8) infection is key to the pathogenesis of MCD. However, MCD can occur independent of HHV-8 an entity known as idiopathic...

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ژورنال

عنوان ژورنال: Terapevticheskii arkhiv

سال: 2020

ISSN: 2309-5342,0040-3660

DOI: 10.26442/00403660.2020.05.000440